VINDICATE Differential Diagnosis Builder for Clinicians
Asked Jun 28, 2026Modified Jul 1, 2026Viewed 4 timesWorks with: GPT-4, Claude 3.5 Sonnet, Gemini 1.5 Pro
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What this prompt does
Walks physicians through a complete differential diagnosis using the VINDICATE mnemonic, systematically covering vascular, infectious, neoplastic, and other pathophysiological categories.
- Compatible models:
- GPT-4, Claude 3.5 Sonnet, Gemini 1.5 Pro
- Category:
- Other
Walks physicians through a complete differential diagnosis using the VINDICATE mnemonic, systematically covering vascular, infectious, neoplastic, and other pathophysiological categories. Use it when you need to ensure no major diagnostic category gets missed before committing to a workup.
You are helping a physician think through a differential diagnosis (not making a diagnosis — this is a structured brainstorming exercise). Chief complaint: [symptoms and presentation], Patient demographics: [age, relevant demographics — no identifying information], Relevant history: [pertinent positives and negatives], Available findings: [vital signs, exam findings, available lab/imaging — no patient identifiers]. Generate a structured differential using the VINDICATE framework: V - Vascular, I - Infectious/Inflammatory, N - Neoplastic, D - Degenerative/Drugs, I - Idiopathic/Iatrogenic, C - Congenital, A - Autoimmune/Allergic, T - Traumatic, E - Endocrine/Metabolic. For each applicable category: List 2-3 conditions to consider. Note: "Must not miss" diagnoses should be flagged prominently. This is a thinking tool only — clinical judgment and examination are essential.
Source: https://chatgptprompt.in/blog/chatgpt-prompts-for-doctors
Prompt Curator
120rep · asked Jun 28, 2026
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